Cargando…

Transcriptome Analyses in BV2 Microglial Cells Following Treatment With Amino-Terminal Fragments of Apolipoprotein E

Despite the fact that harboring the apolipoprotein E4 (APOE4) allele represents the single greatest risk factor for late-onset Alzheimer’s disease (AD), the exact mechanism by which ApoE4 contributes to disease progression remains unknown. Recently, we demonstrated that a 151 amino-terminal fragment...

Descripción completa

Detalles Bibliográficos
Autores principales: Pollock, Tanner B., Cholico, Giovan N., Isho, Noail F., Day, Ryan J., Suresh, Tarun, Stewart, Erica S., McCarthy, Madyson M., Rohn, Troy T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456952/
https://www.ncbi.nlm.nih.gov/pubmed/32922284
http://dx.doi.org/10.3389/fnagi.2020.00256