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Self-Assembly M2e-Based Peptide Nanovaccine Confers Broad Protection Against Influenza Viruses

The extracellular domain of influenza M2 protein (M2e) is highly conserved and is a promising target for development of universal influenza vaccines. Here, we synthesized a peptide vaccine consisting of M2e epitope linked to a fibrillizing peptide, which could self-assemble into nanoparticle in phys...

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Detalles Bibliográficos
Autores principales: Wang, Qimin, Zhang, Yuling, Zou, Peng, Wang, Meixiang, Fu, Weihui, She, Jialei, Song, Zhigang, Xu, Jianqing, Huang, Jinghe, Wu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457018/
https://www.ncbi.nlm.nih.gov/pubmed/32922379
http://dx.doi.org/10.3389/fmicb.2020.01961