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Podocytes Produce and Secrete Functional Complement C3 and Complement Factor H

Podocytes are an important part of the glomerular filtration barrier and the key player in the development of proteinuria, which is an early feature of complement mediated renal diseases. Complement factors are mainly liver-born and present in circulation. Nevertheless, there is a growing body of ev...

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Detalles Bibliográficos
Autores principales: Mühlig, Anne K., Keir, Lindsay S., Abt, Jana C., Heidelbach, Hannah S., Horton, Rachel, Welsh, Gavin I., Meyer-Schwesinger, Catherine, Licht, Christoph, Coward, Richard J., Fester, Lars, Saleem, Moin A., Oh, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457071/
https://www.ncbi.nlm.nih.gov/pubmed/32922395
http://dx.doi.org/10.3389/fimmu.2020.01833