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Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway

The thioredoxin (Trx) system plays critical roles in regulating intracellular redox levels and defending organisms against oxidative stress. Recent studies indicated that Trx reductase (TrxR) was overexpressed in various types of human cancer cells indicating that the Trx-TrxR system may be a potent...

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Detalles Bibliográficos
Autores principales: Hwangbo, Hyun, Kim, So Young, Lee, Hyesook, Park, Shin-Hyung, Hong, Su Hyun, Park, Cheol, Kim, Gi-Young, Leem, Sun-Hee, Hyun, Jin Won, Cheong, Jaehun, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457169/
https://www.ncbi.nlm.nih.gov/pubmed/32856616
http://dx.doi.org/10.4062/biomolther.2020.122