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Telmisartan Inhibits TNFα-Induced Leukocyte Adhesion by Blocking ICAM-1 Expression in Astroglial Cells but Not in Endothelial Cells

Telmisartan is an angiotensin-II receptor blocker and acts as a selective modulator of peroxisome proliferator-activated receptor gamma (PPARγ). Several studies have demonstrated that telmisartan ameliorates depression and memory dysfunction and reduces brain inflammation. We hypothesized that the b...

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Detalles Bibliográficos
Autores principales: Jang, Changhwan, Kim, Jungjin, Kwon, Youngsun, Jo, Sangmee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457170/
https://www.ncbi.nlm.nih.gov/pubmed/32782234
http://dx.doi.org/10.4062/biomolther.2020.119