Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice

Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity. Dasatinib is a type of anti-cancer agent and it has also been reported to inhibit human basophils. However, dasatinib has not been reported for it...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Dajeong, Park, Young Hwan, Lee, Ji Eon, Kim, Hyuk Soon, Min, Keun Young, Jo, Min Geun, Kim, Hyung Sik, Choi, Wahn Soo, Kim, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457176/
https://www.ncbi.nlm.nih.gov/pubmed/32268657
http://dx.doi.org/10.4062/biomolther.2020.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457176/
https://www.ncbi.nlm.nih.gov/pubmed/32268657
http://dx.doi.org/10.4062/biomolther.2020.013

Ejemplares similares