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Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice
Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity. Dasatinib is a type of anti-cancer agent and it has also been reported to inhibit human basophils. However, dasatinib has not been reported for it...
Autores principales: | Lee, Dajeong, Park, Young Hwan, Lee, Ji Eon, Kim, Hyuk Soon, Min, Keun Young, Jo, Min Geun, Kim, Hyung Sik, Choi, Wahn Soo, Kim, Young Mi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457176/ https://www.ncbi.nlm.nih.gov/pubmed/32268657 http://dx.doi.org/10.4062/biomolther.2020.013 |
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