Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome

Activation of the NLRP3 inflammasome is critical for host defense as well as the progression of inflammatory diseases through the production of the proinflammatory cytokine IL-1β, which is cleaved by active caspase-1. It has been reported that overactivation of the NLRP3 inflammasome contributes to...

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Detalles Bibliográficos
Autores principales: Yang, Gabsik, Lee, Seon Joo, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Zouboulis, Christos C., Han, Sin-Hee, Ma, Kyung-Ho, Jang, Jae-Ki, Lee, Joo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457177/
https://www.ncbi.nlm.nih.gov/pubmed/32319265
http://dx.doi.org/10.4062/biomolther.2020.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457177/
https://www.ncbi.nlm.nih.gov/pubmed/32319265
http://dx.doi.org/10.4062/biomolther.2020.004

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