KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of pathological cardiac hypertrophy. To discover novel scaffolds that selectively inhibit GRK5, we have identified a novel smal...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Hyun, Seo, Ho Won, Ryu, Jae Yong, Lim, Chae Jo, Yi, Kyu Yang, Oh, Kwang-Seok, Lee, Byung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457178/
https://www.ncbi.nlm.nih.gov/pubmed/32856617
http://dx.doi.org/10.4062/biomolther.2020.129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457178/
https://www.ncbi.nlm.nih.gov/pubmed/32856617
http://dx.doi.org/10.4062/biomolther.2020.129

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