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Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models

BACKGROUND: Rhesus macaques are valuable pre-clinical models for malaria vaccine development. The Plasmodium knowlesi/rhesus and Plasmodium falciparum/rhesus models are two established platforms for malaria vaccine testing, and both have previously been used to assess live-attenuated sporozoite vacc...

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Detalles Bibliográficos
Autores principales: Shears, Melanie J., Seilie, Annette M., Kim Lee Sim, B., Hoffman, Stephen L., Murphy, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457220/
https://www.ncbi.nlm.nih.gov/pubmed/32867784
http://dx.doi.org/10.1186/s12936-020-03385-4