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Roles of METTL3 in cancer: mechanisms and therapeutic targeting

N(6)-methyladenosine (m(6)A) is the most abundant mRNA modification and is catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is the sole catalytic subunit. Accumulating evidence in recent years reveals that METTL3 plays key roles in a variety of cancer types, eit...

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Detalles Bibliográficos
Autores principales: Zeng, Chengwu, Huang, Wanxu, Li, Yangqiu, Weng, Hengyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457244/
https://www.ncbi.nlm.nih.gov/pubmed/32854717
http://dx.doi.org/10.1186/s13045-020-00951-w