Cargando…
Roles of METTL3 in cancer: mechanisms and therapeutic targeting
N(6)-methyladenosine (m(6)A) is the most abundant mRNA modification and is catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is the sole catalytic subunit. Accumulating evidence in recent years reveals that METTL3 plays key roles in a variety of cancer types, eit...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457244/ https://www.ncbi.nlm.nih.gov/pubmed/32854717 http://dx.doi.org/10.1186/s13045-020-00951-w |