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FGF21 alleviates neuroinflammation following ischemic stroke by modulating the temporal and spatial dynamics of microglia/macrophages

BACKGROUND: Resident microglia and macrophages are the predominant contributors to neuroinflammation and immune reactions, which play a critical role in the pathogenesis of ischemic brain injury. Controlling inflammatory responses is considered a promising therapeutic approach for stroke. Recombinan...

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Detalles Bibliográficos
Autores principales: Wang, Dongxue, Liu, Fei, Zhu, Liyun, Lin, Ping, Han, Fanyi, Wang, Xue, Tan, Xianxi, Lin, Li, Xiong, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457364/
https://www.ncbi.nlm.nih.gov/pubmed/32867781
http://dx.doi.org/10.1186/s12974-020-01921-2