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Novel design of (PEG-ylated)PAMAM-based nanoparticles for sustained delivery of BDNF to neurotoxin-injured differentiated neuroblastoma cells

Brain-derived neurotrophic factor (BDNF) is essential for the development and function of human neurons, therefore it is a promising target for neurodegenerative disorders treatment. Here, we studied BDNF-based electrostatic complex with dendrimer nanoparticles encapsulated in polyethylene glycol (P...

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Detalles Bibliográficos
Autores principales: Dąbkowska, Maria, Łuczkowska, Karolina, Rogińska, Dorota, Sobuś, Anna, Wasilewska, Monika, Ulańczyk, Zofia, Machaliński, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457365/
https://www.ncbi.nlm.nih.gov/pubmed/32867843
http://dx.doi.org/10.1186/s12951-020-00673-8