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Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes

OBJECTIVE: The disruption of metabolic events and changes to nutrient and oxygen availability due to sustained inflammation in RA increases the demand of bioenergetic and biosynthetic processes within the damaged tissue. The current study aimed to understand the molecular mechanisms of SLC7A5 (amino...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Jiang, Congshan, Cai, Yongsong, Guo, Yuanxu, Wang, Xipeng, Zhang, Jiaxiang, Xu, Jiawen, Xu, Ke, Zhu, Wenhua, Wang, Si, Zhang, Fujun, Geng, Manman, Han, Yan, Ning, Qilan, Xu, Peng, Meng, Liesu, Lu, Shemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457370/
https://www.ncbi.nlm.nih.gov/pubmed/32867828
http://dx.doi.org/10.1186/s13075-020-02296-8