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TRPP2 and STIM1 form a microdomain to regulate store-operated Ca(2+) entry and blood vessel tone

BACKGROUND: Polycystin-2 (TRPP2) is a Ca(2+) permeable nonselective cationic channel essential for maintaining physiological function in live cells. Stromal interaction molecule 1 (STIM1) is an important Ca(2+) sensor in store-operated Ca(2+) entry (SOCE). Both TRPP2 and STIM1 are expressed in endop...

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Detalles Bibliográficos
Autores principales: Guo, Jizheng, Zhao, Ren, Zhou, Muyao, Li, Jie, Yao, Xiaoqiang, Du, Juan, Chen, Jiexia, Shen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457527/
https://www.ncbi.nlm.nih.gov/pubmed/32867798
http://dx.doi.org/10.1186/s12964-020-00560-7