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Characterization of thrombin/factor Xa inhibitors in Rhizoma Chuanxiong through UPLC-MS-based multivariate statistical analysis

BACKGROUND: The dry root and rhizome of Ligusticum chuanxiong Hort., or Chuanxiong, has been used as a blood-activating and stasis-removing traditional Chinese medicine for 1000 years. Our previous studies have shown the inhibitory activity on platelet and thrombin (THR) of Chuanxiong. THR and facto...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Yao, Wu, Zhao-Yu, Xia, Fang-Bo, Zhang, Hao, Wang, Xu, Gao, Jian-Li, Yang, Feng-Qing, Wan, Jian-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457533/
https://www.ncbi.nlm.nih.gov/pubmed/32874198
http://dx.doi.org/10.1186/s13020-020-00376-0