AMPK/mTOR/ULK1 Axis-Mediated Pathway Participates in Apoptosis and Autophagy Induction by Oridonin in Colon Cancer DLD-1 Cells

BACKGROUND: Oridonin has been demonstrated to exert strong antitumor activities in various types of human cancers. Our previous study established that oridonin induced the apoptosis of and exerted an inhibitory effect on colon cancer cells in vitro and in vivo. However, the mechanisms behind the ant...

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Detalles Bibliográficos
Autores principales: Bu, Heqi, Liu, Dianlei, Zhang, Guolin, Chen, Li, Song, Zhangfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457577/
https://www.ncbi.nlm.nih.gov/pubmed/32904616
http://dx.doi.org/10.2147/OTT.S262022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457577/
https://www.ncbi.nlm.nih.gov/pubmed/32904616
http://dx.doi.org/10.2147/OTT.S262022

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