Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease

BACKGROUND: Oxidative stress (OS) has been implicated in the development of pulmonary hypertension (PH) and ventricular hypertrophy. Xanthine oxidase is a well-recognised source of reactive oxygen species, which lead to OS. The aim of this proof of concept study was to assess whether allopurinol (xa...

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Detalles Bibliográficos
Autores principales: Liu-Shiu-Cheong, Patrick S K, Lipworth, Brian J, Weir-McCall, Jonathan R, Houston, J Graeme, Struthers, Allan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457596/
https://www.ncbi.nlm.nih.gov/pubmed/32904701
http://dx.doi.org/10.2147/COPD.S260917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457596/
https://www.ncbi.nlm.nih.gov/pubmed/32904701
http://dx.doi.org/10.2147/COPD.S260917

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