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Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease
BACKGROUND: Oxidative stress (OS) has been implicated in the development of pulmonary hypertension (PH) and ventricular hypertrophy. Xanthine oxidase is a well-recognised source of reactive oxygen species, which lead to OS. The aim of this proof of concept study was to assess whether allopurinol (xa...
Autores principales: | Liu-Shiu-Cheong, Patrick S K, Lipworth, Brian J, Weir-McCall, Jonathan R, Houston, J Graeme, Struthers, Allan D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457596/ https://www.ncbi.nlm.nih.gov/pubmed/32904701 http://dx.doi.org/10.2147/COPD.S260917 |
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