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SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia

Global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues unabated. Binding of SARS-CoV-2’s Spike protein to host angiotensin converting enzyme 2 triggers viral entry, but other proteins may participate, including neuropilin-1 receptor (NRP-1). As both Spike protein and...

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Detalles Bibliográficos
Autores principales: Moutal, Aubin, Martin, Laurent F., Boinon, Lisa, Gomez, Kimberly, Ran, Dongzhi, Zhou, Yuan, Stratton, Harrison J., Cai, Song, Luo, Shizhen, Gonzalez, Kerry Beth, Perez-Miller, Samantha, Patwardhan, Amol, Ibrahim, Mohab M., Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457601/
https://www.ncbi.nlm.nih.gov/pubmed/32869019
http://dx.doi.org/10.1101/2020.07.17.209288