Intestinal stenosis in Crohn’s disease shows a generalized upregulation of genes involved in collagen metabolism and recognition that could serve as novel anti-fibrotic drug targets

BACKGROUND AND AIMS: Crohn’s disease (CD) can be complicated by intestinal fibrosis. Pharmacological therapies against intestinal fibrosis are not available. The aim of this study was to determine whether pathways involved in collagen metabolism are upregulated in intestinal fibrosis, and to discuss...

Descripción completa

Detalles Bibliográficos
Autores principales: van Haaften, Wouter Tobias, Blokzijl, Tjasso, Hofker, Hendrik Sijbrand, Olinga, Peter, Dijkstra, Gerard, Bank, Ruud A., Boersema, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457685/
https://www.ncbi.nlm.nih.gov/pubmed/32922514
http://dx.doi.org/10.1177/1756284820952578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457685/
https://www.ncbi.nlm.nih.gov/pubmed/32922514
http://dx.doi.org/10.1177/1756284820952578

Ejemplares similares