B-Cell-Targeted 3DNA Nanotherapy Against Indoleamine 2,3-Dioxygenase 2 (IDO2) Ameliorates Autoimmune Arthritis in a Preclinical Model

The tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase 2 (IDO2) has been identified as an immunomodulatory agent promoting autoimmunity in preclinical models. As such, finding ways to target the expression of IDO2 in B cells promises a new avenue for therapy for debilitating autoimmune disor...

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Detalles Bibliográficos
Autores principales: Merlo, Lauren MF, Bowers, Jessica, Stefanoni, Tony, Getts, Robert, Mandik-Nayak, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457693/
https://www.ncbi.nlm.nih.gov/pubmed/32924009
http://dx.doi.org/10.1177/2632010X20951812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457693/
https://www.ncbi.nlm.nih.gov/pubmed/32924009
http://dx.doi.org/10.1177/2632010X20951812

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