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Malic Enzyme 1 Indicates Worse Prognosis in Breast Cancer and Promotes Metastasis by Manipulating Reactive Oxygen Species

PURPOSE: Malic enzyme 1 (ME1) catalyzes malate to pyruvate and thus promotes glycolysis. Its function in breast cancer remains to be fully clarified. The aim of this work was to investigate the prognostic value of ME1 and its possible mechanism in breast cancer. METHODS: We evaluated ME1 expression...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Cao, Jun, Lin, Shuchen, Zhao, Yannan, Zhu, Mingyu, Tao, Zhonghua, Hu, Xichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457736/
https://www.ncbi.nlm.nih.gov/pubmed/32922044
http://dx.doi.org/10.2147/OTT.S256970