Long Non-Coding RNA KCNQ1OT1 Promotes Multidrug Resistance in Chordoma by Functioning as a Molecular Sponge of miR-27b-3p and Subsequently Increasing ATF2 Expression

BACKGROUND: Chordoma, a rare bone tumor, occurs most commonly at the sacrococcygeal and skull base region. To date, chemotherapy is used to treat patients with advanced-stage chordoma. However, multidrug resistance (MDR) greatly hinders the effect of chemotherapy in chordoma. Here, we studied the co...

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Detalles Bibliográficos
Autores principales: Li, Lei, Lv, Guohua, Wang, Bing, Ma, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457737/
https://www.ncbi.nlm.nih.gov/pubmed/32922083
http://dx.doi.org/10.2147/CMAR.S250611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457737/
https://www.ncbi.nlm.nih.gov/pubmed/32922083
http://dx.doi.org/10.2147/CMAR.S250611

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