Cargando…

Exosomes-Coated miR-34a Displays Potent Antitumor Activity in Pancreatic Cancer Both in vitro and in vivo

PURPOSE: MiR-34a, which acts as an important tumor suppressor gene, plays an important role in pancreatic cancer. However, the therapeutic application of miR-34a is limited by the lack of an effective delivery system. In the present study, we synthesize exosomes-coated miR-34a (exomiR-34a), and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zuo, Ling, Tao, Hongyu, Xu, Huanli, Li, Cong, Qiao, Gan, Guo, Mingyue, Cao, Shousong, Liu, Minghua, Lin, Xiukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457762/
https://www.ncbi.nlm.nih.gov/pubmed/32921986
http://dx.doi.org/10.2147/DDDT.S265423