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Cancer-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to promote lung cancer progression

BACKGROUND: Exosomes are emerging as important mediators of the cross-talk between tumor cells and the microenvironment. The communication between tumor-derived exosomes and macrophages has a critical role in facilitating tumor progression. However, the mechanisms by which exosomes modulate tumor de...

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Detalles Bibliográficos
Autores principales: Liang, Manman, Chen, Xingwu, Wang, Lijing, Qin, Lilong, Wang, Hanli, Sun, Zhengui, Zhao, Wenying, Geng, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457778/
https://www.ncbi.nlm.nih.gov/pubmed/32867817
http://dx.doi.org/10.1186/s13046-020-01688-7