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A Novel Epitope Quality-Based Immune Escape Mechanism Reveals Patient’s Suitability for Immune Checkpoint Inhibition

BACKGROUND: Immune checkpoint inhibition, especially the blockade of PD-1 and PD-L1, has become one of the most thriving therapeutic approaches in modern oncology. Immune evasion caused by altered tumor epitope processing (so-called processing escapes) may be one way to explain immune checkpoint inh...

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Detalles Bibliográficos
Autores principales: Wessolly, Michael, Stephan-Falkenau, Susann, Streubel, Anna, Werner, Robert, Borchert, Sabrina, Griff, Sergej, Mairinger, Elena, Walter, Robert F H, Bauer, Torsten, Eberhardt, Wilfried E E, Blum, Torsten G, Schmid, Kurt W, Kollmeier, Jens, Mairinger, Thomas, Mairinger, Fabian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457781/
https://www.ncbi.nlm.nih.gov/pubmed/32922086
http://dx.doi.org/10.2147/CMAR.S258396