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Multi-level consistent changes of the ECM pathway identified in a typical keratoconus twin’s family by multi-omics analysis

BACKGROUND: Keratoconus (KC) is a common, degenerative disorder of the cornea, and genetic factors play a key role in its development. However, the genetic etiology of KC is still unclear. This study used the family of twins as material, using, for the first time, multi-omics analysis, to systematic...

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Detalles Bibliográficos
Autores principales: Hao, Xiao-dan, Chen, Xiu-nian, Zhang, Yang-yang, Chen, Peng, Wei, Chao, Shi, Wei-yun, Gao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457807/
https://www.ncbi.nlm.nih.gov/pubmed/32867823
http://dx.doi.org/10.1186/s13023-020-01512-7