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Multi-level consistent changes of the ECM pathway identified in a typical keratoconus twin’s family by multi-omics analysis
BACKGROUND: Keratoconus (KC) is a common, degenerative disorder of the cornea, and genetic factors play a key role in its development. However, the genetic etiology of KC is still unclear. This study used the family of twins as material, using, for the first time, multi-omics analysis, to systematic...
Autores principales: | Hao, Xiao-dan, Chen, Xiu-nian, Zhang, Yang-yang, Chen, Peng, Wei, Chao, Shi, Wei-yun, Gao, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457807/ https://www.ncbi.nlm.nih.gov/pubmed/32867823 http://dx.doi.org/10.1186/s13023-020-01512-7 |
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