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Quantitative cytogenetics reveals molecular stoichiometry and longitudinal organization of meiotic chromosome axes and loops

During meiosis, chromosomes adopt a specialized organization involving assembly of a cohesin-based axis along their lengths, with DNA loops emanating from this axis. We applied novel, quantitative, and widely applicable cytogenetic strategies to elucidate the molecular bases of this organization usi...

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Detalles Bibliográficos
Autores principales: Woglar, Alexander, Yamaya, Kei, Roelens, Baptiste, Boettiger, Alistair, Köhler, Simone, Villeneuve, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458323/
https://www.ncbi.nlm.nih.gov/pubmed/32813728
http://dx.doi.org/10.1371/journal.pbio.3000817