Cargando…

Relating SMCHD1 structure to its function in epigenetic silencing

The structural maintenance of chromosomes hinge domain containing protein 1 (SMCHD1) is a large multidomain protein involved in epigenetic gene silencing. Variations in the SMCHD1 gene are associated with two debilitating human disorders, facioscapulohumeral muscular dystrophy (FSHD) and Bosma arhin...

Descripción completa

Detalles Bibliográficos
Autores principales: Gurzau, Alexandra D., Blewitt, Marnie E., Czabotar, Peter E., Murphy, James M., Birkinshaw, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458401/
https://www.ncbi.nlm.nih.gov/pubmed/32779700
http://dx.doi.org/10.1042/BST20200242