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Relating SMCHD1 structure to its function in epigenetic silencing

The structural maintenance of chromosomes hinge domain containing protein 1 (SMCHD1) is a large multidomain protein involved in epigenetic gene silencing. Variations in the SMCHD1 gene are associated with two debilitating human disorders, facioscapulohumeral muscular dystrophy (FSHD) and Bosma arhin...

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Detalles Bibliográficos
Autores principales:	Gurzau, Alexandra D., Blewitt, Marnie E., Czabotar, Peter E., Murphy, James M., Birkinshaw, Richard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458401/ https://www.ncbi.nlm.nih.gov/pubmed/32779700 http://dx.doi.org/10.1042/BST20200242

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