Sustainable Synthesis of a Potent and Selective 5-HT(7) Receptor Antagonist Using a Mechanochemical Approach

[Image: see text] A mechanochemical procedure was developed to obtain PZ-1361, a potent and selective 5-HT(7) receptor antagonist, with antidepressant properties in rodents. The elaborated protocol offered several advantages over classical batch synthesis, including improvement of the overall yield...

Descripción completa

Detalles Bibliográficos
Autores principales: Canale, Vittorio, Frisi, Valeria, Bantreil, Xavier, Lamaty, Frédéric, Zajdel, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458427/
https://www.ncbi.nlm.nih.gov/pubmed/32706254
http://dx.doi.org/10.1021/acs.joc.0c01044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458427/
https://www.ncbi.nlm.nih.gov/pubmed/32706254
http://dx.doi.org/10.1021/acs.joc.0c01044

Ejemplares similares