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Sustainable Synthesis of a Potent and Selective 5-HT(7) Receptor Antagonist Using a Mechanochemical Approach

[Image: see text] A mechanochemical procedure was developed to obtain PZ-1361, a potent and selective 5-HT(7) receptor antagonist, with antidepressant properties in rodents. The elaborated protocol offered several advantages over classical batch synthesis, including improvement of the overall yield...

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Detalles Bibliográficos
Autores principales:	Canale, Vittorio, Frisi, Valeria, Bantreil, Xavier, Lamaty, Frédéric, Zajdel, Paweł
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458427/ https://www.ncbi.nlm.nih.gov/pubmed/32706254 http://dx.doi.org/10.1021/acs.joc.0c01044

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