Matching cell lines with cancer type and subtype of origin via mutational, epigenomic, and transcriptomic patterns

Cell lines are commonly used as cancer models. The tissue of origin provides context for understanding biological mechanisms and predicting therapy response. We therefore systematically examined whether cancer cell lines exhibit features matching the presumed cancer type of origin. Gene expression a...

Descripción completa

Detalles Bibliográficos
Autores principales: Salvadores, Marina, Fuster-Tormo, Francisco, Supek, Fran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458440/
https://www.ncbi.nlm.nih.gov/pubmed/32937430
http://dx.doi.org/10.1126/sciadv.aba1862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458440/
https://www.ncbi.nlm.nih.gov/pubmed/32937430
http://dx.doi.org/10.1126/sciadv.aba1862

Ejemplares similares