Cargando…
Matching cell lines with cancer type and subtype of origin via mutational, epigenomic, and transcriptomic patterns
Cell lines are commonly used as cancer models. The tissue of origin provides context for understanding biological mechanisms and predicting therapy response. We therefore systematically examined whether cancer cell lines exhibit features matching the presumed cancer type of origin. Gene expression a...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458440/ https://www.ncbi.nlm.nih.gov/pubmed/32937430 http://dx.doi.org/10.1126/sciadv.aba1862 |