Cargando…

Emergence of SARS-CoV-2 through recombination and strong purifying selection

COVID-19 has become a global pandemic caused by the novel coronavirus SARS-CoV-2. Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis, discovering new drugs, and developing a vaccine. We show evidence of strong purifying selection around the receptor binding motif (RBM)...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaojun, Giorgi, Elena E., Marichannegowda, Manukumar Honnayakanahalli, Foley, Brian, Xiao, Chuan, Kong, Xiang-Peng, Chen, Yue, Gnanakaran, S., Korber, Bette, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458444/
https://www.ncbi.nlm.nih.gov/pubmed/32937441
http://dx.doi.org/10.1126/sciadv.abb9153