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Suprachoroidal gene transfer with nonviral nanoparticles

Subretinal injections of viral vectors provide great benefits but have limited cargo capacity; they induce innate and adaptive immune responses, which may cause damage and preclude repeated injections; and they pose administration risks. As a new biotechnology, suprachoroidal injections of biodegrad...

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Detalles Bibliográficos
Autores principales: Shen, Jikui, Kim, Jayoung, Tzeng, Stephany Y., Ding, Kun, Hafiz, Zibran, Long, Da, Wang, Jiangxia, Green, Jordan J., Campochiaro, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458446/
https://www.ncbi.nlm.nih.gov/pubmed/32937452
http://dx.doi.org/10.1126/sciadv.aba1606