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Suprachoroidal gene transfer with nonviral nanoparticles
Subretinal injections of viral vectors provide great benefits but have limited cargo capacity; they induce innate and adaptive immune responses, which may cause damage and preclude repeated injections; and they pose administration risks. As a new biotechnology, suprachoroidal injections of biodegrad...
Autores principales: | Shen, Jikui, Kim, Jayoung, Tzeng, Stephany Y., Ding, Kun, Hafiz, Zibran, Long, Da, Wang, Jiangxia, Green, Jordan J., Campochiaro, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458446/ https://www.ncbi.nlm.nih.gov/pubmed/32937452 http://dx.doi.org/10.1126/sciadv.aba1606 |
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