Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer

The murine MC-38 colorectal cancer model is a commonly used model for cancer with high mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to analyze endogenous CD8(+) T cell responses to MC-38 neo-antigens in tumor-bearing mice and after anti-PD-L1 checkpoint thera...

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Detalles Bibliográficos
Autores principales: Hos, Brett J., Camps, Marcel G.M., van den Bulk, Jitske, Tondini, Elena, van den Ende, Thomas C., Ruano, Dina, Franken, Kees, Janssen, George M.C., Ru, Arnoud, Filippov, Dmitri V., Arens, Ramon, van Veelen, Peter A., Miranda, Noel, Ossendorp, Ferry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458608/
https://www.ncbi.nlm.nih.gov/pubmed/32923109
http://dx.doi.org/10.1080/2162402X.2019.1673125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458608/
https://www.ncbi.nlm.nih.gov/pubmed/32923109
http://dx.doi.org/10.1080/2162402X.2019.1673125

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