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Intravital imaging reveals synergistic effect of CAR T-cells and radiation therapy in a preclinical immunocompetent glioblastoma model

Recent advances in novel immune strategies, particularly chimeric antigen receptor (CAR)-bearing T-cells, have shown limited efficacy against glioblastoma (GBM) in clinical trials. We currently have an incomplete understanding of how these emerging therapies integrate with the current standard of ca...

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Detalles Bibliográficos
Autores principales: Murty, Surya, Haile, Samuel T., Beinat, Corinne, Aalipour, Amin, Alam, Israt S., Murty, Tara, Shaffer, Travis M., Patel, Chirag B., Graves, Edward E., Mackall, Crystal L., Gambhir, Sanjiv S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458609/
https://www.ncbi.nlm.nih.gov/pubmed/32923113
http://dx.doi.org/10.1080/2162402X.2020.1757360