Cargando…
Intravital imaging reveals synergistic effect of CAR T-cells and radiation therapy in a preclinical immunocompetent glioblastoma model
Recent advances in novel immune strategies, particularly chimeric antigen receptor (CAR)-bearing T-cells, have shown limited efficacy against glioblastoma (GBM) in clinical trials. We currently have an incomplete understanding of how these emerging therapies integrate with the current standard of ca...
Autores principales: | Murty, Surya, Haile, Samuel T., Beinat, Corinne, Aalipour, Amin, Alam, Israt S., Murty, Tara, Shaffer, Travis M., Patel, Chirag B., Graves, Edward E., Mackall, Crystal L., Gambhir, Sanjiv S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458609/ https://www.ncbi.nlm.nih.gov/pubmed/32923113 http://dx.doi.org/10.1080/2162402X.2020.1757360 |
Ejemplares similares
-
Viral Delivery of CAR Targets to Solid Tumors Enables Effective Cell Therapy
por: Aalipour, Amin, et al.
Publicado: (2020) -
BIMG-13. A NOVEL RADIOPHARMACEUTICAL ([(18)F]DASA-23) TO MONITOR PYRUVATE KINASE M2 INDUCED GLYCOLYTIC REPROGRAMMING IN GLIOBLASTOMA
por: Beinat, Corinne, et al.
Publicado: (2021) -
BIMG-16. TRACKING TTFIELDS-INDUCED ALTERATIONS IN GLIOBLASTOMA METABOLISM WITH [18F]DASA-23, A NON-INVASIVE PROBE OF PYRUVATE KINASE M2 (PKM2)
por: Patel, Chirag, et al.
Publicado: (2021) -
Tumor treating fields (TTFields) impairs aberrant glycolysis in glioblastoma as evaluated by [(18)F]DASA-23, a non-invasive probe of pyruvate kinase M2 (PKM2) expression
por: Patel, Chirag B., et al.
Publicado: (2020) -
ICOS immunoPET enables visualization of activated T cells and early diagnosis of murine acute gastrointestinal GvHD
por: Xiao, Zunyu, et al.
Publicado: (2022)