Angioimmunoblastic T-cell lymphoma-like lymphadenopathy in mice transgenic for human RHOA with p.Gly17Val mutation

A missense mutation in RHOA encoding p.Gly17 Val has been reported to occur frequently in angioimmunoblastic T-cell lymphoma (AITL). Here, we describe a murine model which expresses the human RHOA mutant gene product in a T-cell specific manner and develops AITL-like symptoms. Most transgenic mice f...

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Detalles Bibliográficos
Autores principales: Lee, Gyu Jin, Jun, Yukyung, Yoo, Hae Yong, Jeon, Yoon Kyung, Lee, Daekee, Lee, Sanghyuk, Kim, Jaesang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458614/
https://www.ncbi.nlm.nih.gov/pubmed/32923110
http://dx.doi.org/10.1080/2162402X.2020.1746553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458614/
https://www.ncbi.nlm.nih.gov/pubmed/32923110
http://dx.doi.org/10.1080/2162402X.2020.1746553

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