Generation of highly activated, antigen-specific tumor-infiltrating CD8(+) T cells induced by a novel T cell-targeted immunotherapy

The induction of tumor-targeted, cytotoxic T lymphocytes has been recognized as a key component to successful immunotherapy. DPX-based treatment was previously shown to effectively recruit activated CD8(+) T cells to the tumor. Herein, we analyze the unique phenotype of the CD8(+) T cells recruited...

Descripción completa

Detalles Bibliográficos
Autores principales: Vila-Leahey, Ava, MacKay, Alecia, Portales-Cervantes, Liliana, Weir, Genevieve M., Merkx-Jacques, Alexandra, Stanford, Marianne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458631/
https://www.ncbi.nlm.nih.gov/pubmed/32923145
http://dx.doi.org/10.1080/2162402X.2020.1782574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458631/
https://www.ncbi.nlm.nih.gov/pubmed/32923145
http://dx.doi.org/10.1080/2162402X.2020.1782574

Ejemplares similares