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Modeling human pediatric and adult gliomas in immunocompetent mice through costimulatory blockade
Currently, human glioma tumors are mostly modeled in immunodeficient recipients; however, lack of interactions with adaptive immune system is a serious flaw, particularly in the era when immunotherapies dominate treatment strategies. Our group was the first to successfully establish the orthotopic t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458632/ https://www.ncbi.nlm.nih.gov/pubmed/32923139 http://dx.doi.org/10.1080/2162402X.2020.1776577 |