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Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms

Basophils play an important role in orienting Th2 immune response, and in the pathogenesis of allergic and inflammatory disorders. However, the mechanism by which basophils are kept in check remains unclear and hence we explored the role of regulatory T cells (Treg cells) in this process. We demonst...

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Detalles Bibliográficos
Autores principales: Das, Mrinmoy, Stephen-Victor, Emmanuel, Bayry, Jagadeesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458635/
https://www.ncbi.nlm.nih.gov/pubmed/32923130
http://dx.doi.org/10.1080/2162402X.2020.1773193