Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice

Vaccinia viruses (VACV) are a novel class of immune-oncolytic therapeutics and their mechanism of action is based both on their capacity to replicate selectively in cancer cells and to elicit danger signals that can boost anti-tumor immunity. We recently reported that the intratumor expression of ML...

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Detalles Bibliográficos
Autores principales: Van Hoecke, Lien, Riederer, Stephanie, Saelens, Xavier, Sutter, Gerd, Rojas, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458643/
https://www.ncbi.nlm.nih.gov/pubmed/32923163
http://dx.doi.org/10.1080/2162402X.2020.1802968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458643/
https://www.ncbi.nlm.nih.gov/pubmed/32923163
http://dx.doi.org/10.1080/2162402X.2020.1802968

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