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Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice
Vaccinia viruses (VACV) are a novel class of immune-oncolytic therapeutics and their mechanism of action is based both on their capacity to replicate selectively in cancer cells and to elicit danger signals that can boost anti-tumor immunity. We recently reported that the intratumor expression of ML...
Autores principales: | Van Hoecke, Lien, Riederer, Stephanie, Saelens, Xavier, Sutter, Gerd, Rojas, Juan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458643/ https://www.ncbi.nlm.nih.gov/pubmed/32923163 http://dx.doi.org/10.1080/2162402X.2020.1802968 |
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