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Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

Chimeric antigen receptor (CAR) T cells show remarkable therapeutic effects in some hematological malignancies. However, CAR T cells can also cause life-threatening side effects. In order to minimize off-target and on-target/off-tumor reactions, improve safety, enable controllability, provide high f...

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Detalles Bibliográficos
Autores principales: Feldmann, Anja, Hoffmann, Anja, Bergmann, Ralf, Koristka, Stefanie, Berndt, Nicole, Arndt, Claudia, Rodrigues Loureiro, Liliana, Kittel-Boselli, Enrico, Mitwasi, Nicola, Kegler, Alexandra, Lamprecht, Chris, González Soto, Karla Elizabeth, Bachmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458653/
https://www.ncbi.nlm.nih.gov/pubmed/32923149
http://dx.doi.org/10.1080/2162402X.2020.1785608