Cargando…

Genomic and immunologic correlates of LAG-3 expression in cancer

Immune checkpoint blockade leads to unprecedented responses in many cancers. Although currently available agents mostly target the PD-1 and CTLA-4 pathways, agents targeting the immune checkpoint protein LAG-3 are under active clinical development, and early clinical data show that LAG-3 expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Panda, Anshuman, Rosenfeld, Jeffrey A., Singer, Eric A., Bhanot, Gyan, Ganesan, Shridar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458666/
https://www.ncbi.nlm.nih.gov/pubmed/32923111
http://dx.doi.org/10.1080/2162402X.2020.1756116